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Short Aliphatic Lipid Substitution on Low Molecular Weight Polyethylenimine: Effect on siRNA Complexation from Molecular Dynamics Simulation Studies
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Post transcriptional silencing of aberrant genes with the delivery of short interfering RNA siRNA has been a potent approach to cancer therapy over the last decade...
Diabetic patients suffer from frequent formation of sores on the foot, called diabetic ulcers DU , that are struggling to heal and subject to frequent infections that may require amputation of the lower legs...
The transcription factor Ascl1 plays a key role in neural development and previous work by the Wernig group demonstrated that Ascl1 overexpression using viral vectors can reprogram fibroblasts directly in neurons through the process of cellular reprogramming ADDIN EN...