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Conventional drug screening is performed on cells cultured on 2D, stiff poly styrene , which provides an environment that misrepresents the morphology and growth characteristics of patient tumours...
Adverse tissue reactions are the most common causes of implant failure, they can affect up to 40 of patients with Metal on Metal MoM implants in the first five years of implantation, and a lower but non-negligible number of Metal on Polyethylene MoP and Ceramic on Polyethylene implants 1 ...
Revascularization approaches that involve delivering growth factors with short half-lives minutes over periods of weeks in order to regenerate micro vessels have been identified as promising strategies to address disorders related to compromised tissue perfusion...
Over 80 of metastatic bone disease is caused by breast, prostate, lung, and kidney cancer. The spine is the most common site for metastasis to the bones 1 ...
Currently, it is still a tough task for dentists to remineralize dentine in deep caries. The aim of this study was to remineralize human completely demineralized dentine using nanocomplexes of carboxymethyl chitosan amorphous calcium phosphate CMC ACP based on mimicking the stabilizing effect of dentine matrix protein 1 DMP1 on ACP in the biomineralization of dentine...