A novel electroconductive nanocomposite for in vitro applications in neural tissue engineering
Supervisor: Dr. Fabio Variola
Neurodegenerative conditions and traumatic brain/spinal injuries are associated with neuron loss. Current research aims to develop biomaterials that functionally mimic neural tissues in order to predictably control key cellular events & address these disorders but faces challenges. I aim to investigate mechanisms of neural function by exploring how neurons interact with a newly developed nanocomposite vs. pristine collagen/Matrigel. This will elucidate the role of carbon nanodots in neuron responses & reveal our biomaterial's commercial/industrial value.
Keywords: Collagen, Matrigel, Carbon Nanodots, Electroconductive, Neurodegeneration, Neural Tissue Engineering
Techniques: Multi-electrode Array, Calcium Imaging, Immunofluorescence
Amanie Salama
Contact Information
- University of Ottawa
Department of Mechanical Engineering - 101-360 Frank Street,
Ottawa, Ontario, K2P0Y2 - Email: asala074@uottawa.ca
- Home: 6477020832
- Membership#C243019
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