Multilayer Tissue Scaffolds as Barrier Membranes in Periodontal Regeneration
Supervisor: Todd Hoare
Periodontal disease affects nearly 19% of adults worldwide, yet current regenerative membranes show limited clinical performance. This study developed multilayer electrospun zwitterionic DMAPS-based scaffolds as potential periodontal barrier membranes. Aldehyde- and hydrazide-functionalized DMAPS were successfully electrospun into stable multilayer structures with uniform fiber morphology and minimal degradation over seven days. These findings highlight DMAPS scaffolds as promising candidates for next-generation periodontal regenerative membranes.
Keywords: Periodontal disease, zwitterionic polymers, scaffold, barrier membrane, tissue engineering
Equipment: Syringe pumps, collectors, voltage generator.
Techniques: Electrospinning, SEM,
Alexis Larios Cervantes
Contact Information
- McMaster University
Department of Biomedical Engineering - 1280 Main street west,
Hamilton, L8S 4L8 - Email: lariosca@mcmaster.ca
- Membership#C263233
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