Ex vivo gene therapy and tissue engineering for the treatment of RDEB
Supervisor: Lucie Germain
We aim to close chronical skin wounds of recessive dystrophic epidermolysis bullosa patients using a combination of tissue engineering, relying on the use of the self-assembly approach developped at the LOEX, with retroviral gene therapy to correct for the expression of type VII collagen and therefore, restore a normal skin phenotype after graft.
Keywords: Skin, Gene therapy, Epidermolysis bullosa
Techniques: Immunofluorescence, Flow Cytometry, Viral transduction, Skin self assembly
Martin Barbier
Contact Information
- Université Laval
Department of Faculté de Médecine - 750 Rue Des Lilas E, Appt 3,
Québec, Quebec, G1J1B2 - Email: martin.barbier@crchudequebec.ulaval.ca
- Home: 0767929927
Follow us on Twitter @CanBiomatSoc
Biomaterial Highlight Of The Month
Blood Compatibility of Degradable Polar Hydrophobic Ionic Polyurethane (D-PHI) Designed for Blood Contact Applications
Kathryne Brockman
Read More
