Ex vivo gene therapy and tissue engineering for the treatment of RDEB
Supervisor: Lucie Germain
We aim to close chronical skin wounds of recessive dystrophic epidermolysis bullosa patients using a combination of tissue engineering, relying on the use of the self-assembly approach developped at the LOEX, with retroviral gene therapy to correct for the expression of type VII collagen and therefore, restore a normal skin phenotype after graft.
Keywords: Skin, Gene therapy, Epidermolysis bullosa
Techniques: Immunofluorescence, Flow Cytometry, Viral transduction, Skin self assembly
Martin Barbier
Contact Information
- Université Laval
Department of Faculté de Médecine - 750 Rue Des Lilas E, Appt 3,
Québec, Quebec, G1J1B2 - Email: martin.barbier@crchudequebec.ulaval.ca
- Home: 0767929927
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