Canadian Biomaterials Society
Société Canadienne des Biomatériaux

Increasing growth factor bioavailability from tissue allografts

Supervisor: Sean Peel

Bone matrix contains numerous growth factors. When it is demineralized it can become osteoinductive. However the osteoinductivity of bone matrix is variable. One limitation is the limited bioavailabilty of the growth factors. This project is aimed at improving the osteoinductivity of bone allografts by increasing the bioavailability of the growth factors in the matrix.

Keywords: Bone allograft; bone morphogenetic proteins; BMP; bioavailability

URL: www.inducebiologics.com

Sean Peel

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