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Localized Delivery of Exogenous C-type Natriuretic Peptide from Heparin-Coated NPs – Potential Use in Suppressing Fibrotic Phenotypes in Cardiac Myofibrogenesis
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In a healthy heart, cells naturally secrete C-type natriuretic peptide CNP , an anti-fibrotic cytokine that has strong effects on cardiac fibroblast function, fibrosis, and extracellular matrix deposition...
Differentiation of Mononuclear Cells From Cord Blood in Endothelial Cells Forming Colony Onto Bioactive Poly(ethylene terephthalate) Film for In Situ Endothelialization
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Cardiovascular diseases are one of the leading causes of mortality worldwide. When the replacement of diseased arteries is needed, vascular surgeons often have no choice but to use synthetic arterial prostheses made either of poly ethylene terephthalate PET or Dacron or expanded tetrafluoroethylene ePTFE or Teflon ...
Arterial bypass graft is the primary therapy for patients with advanced vascular occlusion diseases and, in recent years, the development of tissue-engineered vascular grafts has emerged as a promising, clinically applicable alternative to autografts...
Modern medicine relies on the efficient delivery of drugs to treat infections and diseases. Ideally, these drugs should be administered at the exact concentration needed, target the affected area only and not harm healthy cells or tissues...
Osteoclasts play an important role in bone remodelling process1. An in vitro assay that could assess the functions of osteoclasts, is critical for understanding the process of bone resorption and the effectiveness of anti-osteoporotic drugs...
TIER 2 CANADA RESEARCH CHAIR IN CELL ENGINEERING AND BIOMANUFACTURING more
Assistant, Associate, or Full Professor in Bioprocessing and Biomanufacturing more
Research Associate in Next-Generation RNA Therapeutics at UBC more
Research Associate in Next-Generation RNA Therapeutics at UBC more
Recent Member Projects
Élie Daoust: Optimization of a test bench for the evaluation of blood embolizing agents for arterial and venous applications more
Yann Bami-Chatenet: Multifunctional and injectable core-shell microspheres for cell therapy and endovascular treatments more
Alexis Larios Cervantes: Multilayer Tissue Scaffolds as Barrier Membranes in Periodontal Regeneration more
Mahdokht Akbari Taemeh: Developing Plant-based Microcarriers for Scalable Production of Therapeutic Cells more
Recent Member Publications
Kate MacQuarrie: Smooth muscle cell-like support cells accelerate the autologous endothelialization of a polyurethane scaffold for vascular engineering more
Alma Tamunonengiofori Banigo: Bioactive Hydrogels Based on Tyramine and Maleimide Functionalized Dextran for Tissue Engineering Applications more
Alma Tamunonengiofori Banigo: Injectable hydrogels for cartilage tissue engineering: key design needs toward clinical applications more
Alma Tamunonengiofori Banigo: Hydrogel-Based Bioinks for Coaxial and Triaxial Bioprinting: A Review of Material Properties, Printing Techniques, and Applications more