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The monocyte-derived macrophage is one of the first cell types found on newly implanted devices and is known to play a role in inflammation, immunoregulation and wound healing depending on its functional phenotype...
Tissue engineering applies a combination of material, mechanical, chemical and biological sciences with the aim of creating systems that are able to repair of even replace a biological function...
Random and Aligned Electroapun PET Nanofibers: the Roles of Topography and Bioactive Coatings for Complete, Stable Endothelialization of Vascular Grafts
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There have been considerable efforts to develop prosthetic small-diameter below 6mm vascular grafts VGs as an alternative to autologous grafts to bypass or replace occluded blood vessels...
Uncontrolled bleeding causes significant morbidities and mortalities worldwide1. The native blood coagulation is insufficient to halt severe bleeding due to the slow process 2-8 minutes and the weak mechanical properties of blood clots...
Vascular tissue engineering usually relies on the cellularization of scaffold materials with vascular cells with the ultimate aim to produce artificial blood vessels substitutes overcoming the drawbacks of current vascular grafts, especially for small diameter vessels...